Discovering findings and scientific outputs of the CORONADX project
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Point-of-care devices for pathogen detections: The three most important factors to realise towards commercializationScientific publications — 27 Aug 2020
The development of lab-on-a-chip technology and its applications in biochemical and biomedical analyses has, during the last two decades, led to the potential realisation of portable and on-site detection devices, the so-called point-of-care (PoC) detection systems. These are essentially cheap, easy-to-handle systems, offering rapid sample-to-answer results to non-technical operators. In this perspective, we do not review all the current advances of Lab-on-a-chip techniques for the realisation of PoC. Instead, we aim to provide insight into what we foresee as the three most important factors to play the essential roles for succeeding in making commercially viable PoC pathogen-detection devices. The three insights are namely: the utilizations of (i) disposable polymer (microfluidic) chips, (ii) the implementation of surface-bound (or solid-phase) nucleic-acid amplification techniques and (iii) relying (more) on open-source hardware and software.
The spread of COVID-19 in six western metropolitan regionsScientific publications — 12 Apr 2020
Analysis of the spread of the COVID-19 epidemic in 6 metropolitan regions with similar demographic characteristics, daytime commuting population and business activities: the New York metropolitan area, the Île-de-France region, the Greater London county, Bruxelles-Capital, the Community of Madrid and the Lombardy region. The highest mortality rates 30-days after the onset of the epidemic were recorded in New York (81.2 x 100,000) and Madrid (77.1 x 100,000). Lombardy mortality rate is below average (41.4 per 100,000), and it is the only situation in which the capital of the region (Milan) has not been heavily impacted by the epidemic wave. The study analyzed the role played by containment measures and the positive contribution offered by the hospital care system.
2019 Novel Coronavirus Disease (COVID-19): Paving the Road for Rapid Detection and Point-of-Care DiagnosticsScientific publications — 14 Mar 2020
We believe a point-of-care (PoC) device for the rapid detection of the 2019 novel Coronavirus (SARS-CoV-2) is crucial and urgently needed. With this perspective, we give suggestions regarding a potential candidate for the rapid detection of the coronavirus disease 2019 (COVID-19), as well as factors for the preparedness and response to the outbreak of the COVID-19.